Automatic Liquid-Liquid Extraction (LLE) System Applications
The VERSA Automated Liquid-Liquid Extraction (LLE) System, also known as an automated solvent extractor, offers superior flexibility and throughput, automating solvent extractions for toxicology, clinical research, pharmaceuticals, and more. Designed for efficiency and precision, VERSA optimizes workflows with:
- ReagentDrop Bulk Dispensing Module – Dispenses solvents (including organic solvents) and reagents without tips, preventing drips.
- On-deck Tube/Plate Shaker – For efficient mixing and reconstitution.
- Heater Assisted Nitrogen Dryer – Provides a complete walk-away solution.
- Versatile Labware – Adaptors for microcentrifuge tubes, test tubes, vials, and more.
The VERSA system is highly scalable to meet various throughput and budget needs. It automates drug, metabolite, and biomolecule extractions (e.g., lipids and proteins) from biological samples. Contact us for more information.
- Sports Medicine
- Vitamin D from Blood/Serum Samples
- Drugs of Abuse in Forensic Analysis
- Compounds for Drug Discovery
- Iso-Flavonoides from Urine Samples
- Aflatoxins from Seafood Products
- Lipid Extraction
- Growth Promoters in Blood
- Semi-Volatile or Non-Volatile Analytes
Specifications | VERSA110 | VERSA1100 |
| Deck Capacity | 8 | 15 |
| Pipetting Head (Single Channel Function, Disposable Tip) | Single channel with dual syringe pump | 4 or 8 channel |
| ReagentDrop | up to 4 | up to 8 |
| Supported Labware Formats | 24, 48 test-tubes/vials and 96 deep well plates | 24 test-tubes/vials and 96 deep well plates |
| Gripper / Plate Transporter | Plate Transporter | Gripper |
| Reagent Block / Flat Plate Coolers | Either | Either |
| Nitrogen Dryer | N/A | 24 or 96 channels |
| Shaker-Heater (2400rpm, RT to 90°C) | Included | Included |
| Liquid Level Sensing | Optional | Optional |
| HEPA/UV/LED Enclosure | Optional | Optional |
| Width x Depth x Height (cm) | 59 x 66 x 90 | 99 x 75 x 90 |
| Weight (kg) | 40 | 162 |
Independently Validated
Phytoestrogenic isoflavonoids in epidemiologic and clinical research
View the paper to see how the VERSA automated Liquid-Liquid Extraction system is used to to study phytoestrogenic isoflavonoids.
Automated Liquid-Liquid Extraction of Copper using ACORGA® Reagent on a VERSA Mini LLE Workstation
Validation of Automated Extraction (Partition Chromatography) of β-Carotene using VERSA Mini Liquid-Liquid Extraction Workstation
What is the throughput?
It can be configured for 24-sample or 96-well format depending on instrument channels (4 or 8-channel head) – actual throughput time will depend on the specific procedure and steps involved.
Does the instrument come with its own nitrogen supply or does it use the lab’s?
The workstation’s nitrogen dryer has to be connected to the overall lab’s nitrogen supply for any drying step.
What liquids are compatible?
a. For ReagentDrop – most organic solvents are compatible – avoid concentrated aqueous solutions (salting out could clog the tubing) and concentrated acids or bases (can degrade metal components).
b. For pipetting and solutions on deck – avoid very volatile solvents and any concentrated acids or bases (fumes can degrade instrument components).
What is the sample handling volume?
a. Pipette maximum aspiration/dispensing volume is 1000uL.
b. Samples handling is around 10-15 mL.
Can the samples and solvent be kept cool?
Yes, we have cooler/heater flat plates that can bring down the temperature to 4 oC.
What sample sizes/consumables are compatible?
We have custom fabrication/3D printing abilities to meet whatever your needs.
What if my solvent is not compatible with polypropylene pipette tips?
We can offer a steel-pin system (4 or 8-channel, up to 1000 uL) system.
Is barcode tracking available?
Barcode tracking is optional.
How long will it take to dry 10 mL of an organic solvent by the nitrogen dryer for LLE?
If it is around 10 mL, it would take between 20-30 minutes. If it is less than 10 mL then around 10-15 minutes.