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Automated Microarray Spotter Overview

PRODUCT INFORMATION


    Fast, accurate, and flexible microarray printing for peptides, DNA, and cells.

    Aurora’s VERSA™ microarray spotter combines SPOT synthesis with advanced liquid handling to deliver reliable, automated array printing. Designed for combinatorial chemistry, the system supports both contact and non-contact spotting, handling reagents from grams to milligrams.

    Equipped with a nano-pipettor head, it simplifies precise reagent distribution—ideal for peptide synthesis and other high-precision microarray applications.

    High-Throughput Reagent Spotting
    Drug-Eluting Microarray
    Peptide Synthesis
    Tissue Microarray

    CHIP Production
    Cancer Research
    Precision Medicine

    DNA Microarray
    Protein Microarray
    Biomedical Imaging

    VERSA 10 with hood– Compact Automated Liquid Handling Workstation. This robotic liquid handler can conduce qPCR and PCR Set-up Sequencing Reaction Set-up Nucleic Acid Purification Microarray Spotting Immuno and Biochemical Assays Cell-Based Assays Environmental Sample Preparation General Liquid Handling – dilution, plate reformatting, and aliquoting. For 96 well plates and 384 well plates.

    VERSA™ for Cell
    Single Channel
    Small and Compact
    40 nL – 100 µL Spotting Volume
    0.05 mm Positioning Error
    Optional UV/HEPA Enclosure
    Compatible with all Slide Types
    Optional Humidity Control

    VERSA 110 with HEPA/UV/LED Hood – This single-channel automated liquid handling platform with precise XYZ targeting, dual pump pipetting module, DNA and Cells

    VERSA™ for Peptide
    Single Channel
    Increased Deck Area
    40 nL – 100 µL Spotting Volume
    0.05 mm Positional Error
    Optional UV/HEPA Enclosure
    Optional Sonicated Wash station
    Optional Humidity Control

    VERSA-1100, Automated liquid handling System, with 15-positioned modular deck configuration with options such as magnetic bead vortex, shaker-heater and ReagentDrop, For 96 well plates and 384 well plates.

    VERSA™ for DNA
    10, 20 or 35 Channel
    Simultaneous Peptide Spotting
    Bulk Peptides Quickly Constructed
    Heavily Customizable
    Optional UV/HEPA Enclosure
    Compatible with all Slide Types
    Optional Humidity Control

    VERSA-1100, Automated liquid handling System, with 15-positioned modular deck configuration with options such as magnetic bead vortex, shaker-heater and ReagentDrop, For 96 well plates and 384 well plates.

    DNA Microarray Spotter – High-Precision Automated Printing

    The VERSA™ 1100 35-channel automated microarrayer uses a robotic spot printing technique for cDNA microarray assays, enabling both contact and non-contact dispensing of volumes as low as 30 nL. Designed for DNA and RNA applications, it features a fixed pipetting pin system and is optimized for nylon membrane formats.

    Microarray Spotting Highlights:

    • Volume: ~300 nL per spot (∅ ~2 mm)
    • Sample: nucleic acids
    • Surface: nylon membrane, 3 mm spacing

    In applications such as DiagCor’s disease differentiation assays, fluorescently labeled cDNA strands hybridize on the array. Non-specific bindings are washed away using ReagentDrop™, leaving behind high-affinity matches. The resulting fluorescence signal is quantified via downstream analyzers for data normalization and interpretation.

    Application Areas:

    • Gene expression profiling
    • SNP detection and polymorphism analysis
    • Genetic disease diagnostics
    • Non-invasive prenatal testing
    • Forensics, oncology, and drug-target discovery

    With its precision and flexibility, the VERSA™ DNA Microarray Spotter enables efficient, high-throughput genomic analysis across clinical and research settings.

    VERSA 110 with HEPA/UV/LED Hood – This single-channel automated liquid handling platform with precise XYZ targeting, dual pump pipetting module, DNA and Cells

    The VERSA™ 110 Automated Microarrayer simplifies peptide synthesis using Fmoc-based solid-phase chemistry, combined with low-cost porous membrane substrates and intuitive software for easy setup and control.

    Optimized for the SPOT technique, VERSA™ 110 enables high-throughput, high-density peptide microarray printing with volumes as low as 40 nL—ideal for precise pipetting of amino acids and reagents.

    “Stable and reliable—we’ve had zero breakdowns in years. VERSA™ offers higher density, faster printing, and greater accuracy at a lower cost.”
    – User Testimonial

    Background
    Solid-phase peptide synthesis (SPPS) links amino acids via peptide bonds on a solid support. This method enables the production of complex or unnatural peptides, backbone modifications, and sequences not easily expressed in biological systems.

    VERSA 10 with hood– Compact Automated Liquid Handling Workstation. This robotic liquid handler can conduce qPCR and PCR Set-up Sequencing Reaction Set-up Nucleic Acid Purification Microarray Spotting Immuno and Biochemical Assays Cell-Based Assays Environmental Sample Preparation General Liquid Handling – dilution, plate reformatting, and aliquoting. For 96 well plates and 384 well plates.

    At National Taiwan University, the VERSA™ system is used to print cell microarrays onto microscope slides for studying cell signaling pathways and drug binding interactions.

    Printing Specifications:

    • Spotting volume: 100–300 nL per spot (∅ ~2 mm)
    • Sample type: Uniform or varied cell solutions
    • Format: 10×10 array on 15×15 mm microscope cover glass

    After spotting cells, drug molecules are applied to the array. Following incubation, cell morphology is analyzed under a microscope to assess drug effects and pathway activity.

    Independently Validated

    Human germinal centres engage memory and naive B cells after influenza vaccination

    View this publication to see how the VERSA™ 10 Microarray Spotter was used to study immune responses after influenza vaccination.

    Facilitating tumor spheroid-based bioassays and in vitro blood vessel modeling via bioinspired self-formation microstructure devices

    View this publication to see how the VERSA™ 10 Microarray Spotter was used in dispensing water droplets of specific volumes to study how surface tension guides aqueous molding.

    Development of an influenza virus protein microarray to measure the humoral response to influenza virus infection in mallards

    View this open-source publication to see how Influenza virus hemagglutinin (HA) protein was printed in microarrays on epoxysilane-coated glass slides using VERSA™ 110 Microarray Spotter.

    A nanodroplet cell processing platform facilitating drug synergy evaluations for anti-cancer treatments

    Learn more about how the VERSA™ 10 Microarray Spotter was used to develop a nanodroplet cell processing platform for anti-cancer drug synergy.

    Scientific Reports -

    For More Validations or Publications

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