Speaking Program and Schedule
14th November 2018
8:00 AM – 10:00 AM – Registration
10:00 AM – 10:05AM – Opening Remarks: Aurora Biomed Inc.
10:05 AM – 10:15AM – Welcoming Remarks: Shunde Government
10:15 AM – 10:25AM – Welcoming Remarks: Senior Trade Commissioner & Canadian Consulate
10:25 AM – 10:30AM – Welcoming Remarks: Shunde Government
Keynote Presentation
10:35 AM – 11:15AM – Andre Ghetti
CEO of AnaBios Corperation – “Novel Strategies for Translational Research in Pain Drug Discovery”
IC Session:
11:15 AM – 11:45 AM – Xi Huang
Principal Investigator,The Arthur and Sonia Labatt Brain Tumour Research Centre- “From fly to mammal: targeting ion channels in brain tumor”
11:45 AM – 12:05 PM – Wen Yang
Principal Associate, Roche – “Development of an ion flux assay & HTS campaign for modulators of a cation-chloride co-transporter”
12:05 PM – 1:30 PM – Lunch
Parallel Sessions begin
-Start of Parallel Session 1-
PM Session: Precision drug research and development
1:30 PM – 1:35 PM – Chair: Hailong An
Hebei University of Technology
1:35 PM – 1:55 PM – Hailong An
Hebei University of Technology– “Identification of the calcium-dependent gating and targeted-drug discovery of CaCCs”
1:55 PM – 2:15 PM – Erika Piedras-Renteria
Loyola University Chicago– “Leptin-induced hypothalamic excitability is mediated by a TRPC-Cav3 complex”
2:15 PM – 2:35 PM – Wei Yang
Zhejiang University– “TRPM2 Channel: New drug target for treating brain ischemia”
2:35 PM – 3:05 PM – Coffee Break & Posters
PM Session: Novel Targets in Oncology Diagnosis & Treatment
3:05 PM – 3:10 PM – Chair: Saverio Gentile
University of Illinois at Chicago
3:10 PM – 3:30 PM – Saverio Gentile
University of Illinois at Chicago– “Cancer vulnerability unveiled by targeting ion channels: A novel discovery and therapeutic approach”
3:30 PM – 3:50 PM – Cesare Sala
University of Florence – “The ion channel and transporters gene expression profile indicates a shift in excitability and metabolisms during malignant progression of Follicular Lymphoma”
3:50 PM – 4:10 PM – Qinghuan Xiao
China Medical University School of Medicine– “TMEM16A inhibition represents a novel therapy for breast cancer with EGFR expression”
4:10 PM – 4:30 PM – Anna Borgstroem
Transcure, Bern University – “Investigation of TRPM4 and its Role in Cell Migration and Proliferation of Prostate Cancer Cells”
-End of Parallel Session 1-
-Start of Parallel Session 2-
IC Session: Biology Drug – A Potential Therapeutic for Ion Channel Targets
1:30 PM – 1:35 PM – Chair: George Chandy
Nanyang Technological University
1:35 PM – 1:55 PM – George Chandy
Nanyang Technological University – “Immunomodulatory peptides from edible plants”
1:55 PM – 2:15 PM – Yan Nian
Kunming institute of zoology – “Discovery of Novel Natural Products Targeting Ion Channels”
2:15 PM – 2:35 PM – Paul Li
Simon Fraser University – “Activation of TRPV2 on a single glioblastoma cell measured in a microfluidic biochip”
2:35 PM – 3:05 PM – Coffee Break & Posters
IC Session: Human induced pluripotent stem cell-derived cardiomyocytes: From cardiac safety to disease modeling
3:05 PM – 3:10 PM – Chair: Marc Pourrier
IonsGate Preclinical Services Inc
3:10 PM – 3:30 PM – Marc Pourrier
IonsGate Preclinical Services Inc– “Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) to model arrhythmogenic diseases”
3:30 PM – 3:50 PM – Ronald Li
Novoheart– “Engineering Mini Human Heart Chambers for Drug Discovery and Disease Modeling”
3:50 PM – 4:10 PM – Robert Kass
Columbia University– “Patient-specific induced pluripotent stems as a platform for precision therapeutics in the treatment of an inherited cardiac arrhythmia”
4:10 PM – 4:30 PM – Haiheng Dong
Wuxi. Apptech– “The application of human-induced pluripotent stem cell-derived ventricular cardiomyocytes generated in the chemical-defined and albumin-free condition (CaulisCells) in the MEA cardiac safety assessment”
-End of Parallel Session 2-
4:30 PM – 4:40 PM – 10 minute break
Investment Workshop
4:05 PM – 3:10 PM – Chair: Wayne Tan
Executive Director of HK Bio-Med Innotech Association
4:45 PM – 6:30 PM
VIP Dinner
6:30 PM – 9:00 PM
15th November 2018
8:25 AM – 8:30 AM – Welcome & Opening Remarks + Chair of keynote speech: Andre Ghetti
Keynote Presentation
8:30 AM – 9:10 AM – David Smith
Mayo Clinic- “What is the $100 Genome and why is it such a big deal”
Aurora Biomed Presentation
9:10 AM – 9:40 AM – Dong Liang
Aurora Biomed- “Ion Channels Targeted and Anti-Cancer Drug Discovery”
Peptide Array
9:40 AM – 10:00 AM – Myriame Gabay
Biomime Solutions- “Peptide arrays for drug discovery”
10:00 – 10:40 – Coffee Break & Posters
-Start of Parallel Session 1-
PM Session: Novel Targets in Oncology Diagnosis & Treatment
10:40 AM – 10:45 AM – Chair: Annarosa Arcangeli
University of Florence
10:45 AM – 11:05 AM – Chair: Annarosa Arcangeli
University of Florence- “Ion channels in Cancer: from molecular devices to therapeutic targets”
11:05 AM – 11:25 AM – Navin Verma
Nanyang Technological University – “Overriding ‘ionic-checkpoint’: A new strategy to boost antitumour responses of T lymphocytes”
11:25 AM – 11:45 PM – N. Prevarskaya
University of Lille, France – “Calcium and calcium channels in initiation and progression of prostate cancer”
11:45 AM – 12:05 PM – Luigi Leanza
University of Padova, Italy – “Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo”
12:05 PM – 1:05 PM – Lunch
PM Session: Advances of cancer complementary diagnostics and precision therapy
1:05 PM – 1:10 PM – Chair: Frank Fan
1:10 PM – 1:30 PM – Jodie Tang
Zhuhai Livzon Cynvenio Diagnostics Ltd – “Liquid Biopsy: Connecting the missing links of precision medicine in cancer”
1:30 PM – 1:50 PM – Danyi Wen
LIDE Biotech – “Functional Diagnostics and RWE in Cancer Precision Medicine”
1:50 PM – 2:10 PM – Rudy Zhao
Promega – “Application of Microsatellite Instability Analysis in Cancer Diagnosis and Treatment”
PM Session: Novel Tools/Methods to Forensic Sciences & Human Identification
2:10 PM – 2:15 PM – Chair: Helena Wong
Oakland Police department, USA
2:15 PM – 2:35 PM – Helena Wong
Oakland Police department, USA– “Automated Differential Digestion using the VERSA 1100”
2:35 PM – 2:55 PM –
AGCU ScienTech Incorporation– “The application of new products in human identification in challenging cases”
2:55 PM – 3:15 PM – Shujin Li
College of Forensic Medicine Hebei Medical University– “Screening of high-effective DNA methylation markers for discriminating monozygotic twins”
-End of Parallel Session 1-
-Start of Parallel Session 2-
IC Session: The development of anti-tumor drug
10:40 AM – 10:45 AM – Chair: Xi Huang
The Hospital for Sick Children, Toronto
10:45 AM – 11:05 AM – Roger Abounader
University of Virginia– “Role and therapeutic targeting of T-type calcium channels in glioblastoma”
11:05 AM – 11:25 AM – Juri Reimand
Ontario Institute for Cancer Research– “Integrative analysis of pan-cancer genomics datasets reveals prognostic and functional oncochannels”
11:25 AM – 11:45 AM – Chi-chung Hui
The Hospital for Sick Children, Toronto– “GLI2-regulated ion-channel genes as potential targets of SHH medulloblastoma”
11:45 AM – 12:05 PM – Rongqi Huang
GIBH – “Thermal stress promote tumorigenesis in ESCC via TRPV2-dependent pathway”
12:05 PM – 1:05 PM – Lunch
IC Session: Emerging Areas of Ion Transporter Research
1:05 PM – 1:10 PM – Jinwei Zhang
University of Exeter
1:10 PM – 1:30 PM – Dandan Sun
University of Pittsburgh – “Ion transporters in glioma cancer”
1:30 PM – 1:50 PM – Jinwei Zhang
University of Exeter – “KCC2 ion transporter as a novel therapeutic target for epilepsy”
1:50 PM – 2:10 PM – Xianming Deng
School of Life Sciences, Xiamen University – “Pharmacological validation of new kinases with small molecules”
IC Session: Ion Channels Screening Technologies
2:10 PM – 2:15 PM – Andrea Bruggemann
Nanion Technologies GmbH
2:15 PM – 2:35 PM – Andrea Bruggemann
Nanion Technologies GmbH – “Opening up new opportunities by combining high throughput electrophysiology with optical tools”
2:35 PM – 2:55 PM – Shouming Du
Hammatsu – “Case studies: An outsider’s view on phenotypic screening to target identification with a focus on high throughput tools related to ion channels”
-End of Parallel Session 2-
3:15 PM – 3:30 PM – Coffee Break & Posters
Panel Discussion
3:30 PM – 4:30 PM
Boat Cruise + Dinner
4:30 PM – 9:30 PM
16th November 2018
-Start of Parallel Session 1-
PM Session: Applications & Advancement of NGS
9:00 AM – 9:05 AM – Chair: Hui Jiang
BGI
9:05 AM – 9:25 AM – Hui Jiang
BGI – “The application of MGI Sequencers on oncology test”
9:25 AM – 9:45 AM – Issac Garcia- Murillas
The Institute of Cancer Research – “Clinical utility of circulating tumour DNA analysis in hormone receptor positive breast cancer patients”
9:45 AM – 10:05 AM – Xingfei Deng
Ardent Biomed Guangzhou Inc.
10:25 AM – 10:55 AM – Coffee Break & Posters
IC Session: Structure and Function of Ion Channels
10:55 AM – 11:00 AM – Chair: Henry Colecraft
Columbia University
11:00 AM – 11:20 AM – Bailong Xiao
Tsinghua University – “Structure & mechanogating mechanism of the mechanosensitive Piezo1 channel”
11:20 AM – 11:40 AM – Shiqing Cai
Institute of Neuroscience Chinese Academy of Sciences – “The mechanism underlying protein biogensis of the hERG channel and pharmacological rescue of LQTS mutant channels”
11:40 AM – 12:00 PM – Henry Colecraft
Columbia University – “Design and application of genetically-encoded ion channel modulators”
12:00 PM – 12:20 PM – Panpan Hou
Washington University – “A non-canonical VSD-pore coupling in KCNQ channels”
-End of Parallel Session 1-
-Start of Parallel Session 2-
IC Session: Ion Channels as Pain Targets
9:00 AM – 9:05 AM – Chair: Guangyin Xu; Andre Ghetti
Suzhou University
9:05 AM – 9:25 AM – Guangyin Xu
Suzhou University – “Epigenetic regulations of purinergic receptors in various pain conditions”
9:25 AM – 9:45 AM – Joel Castro
Head of Colon Research, Visceral Pain Group (VIPER) – “Contribution of membrane receptors to visceral pain sensation”
9:45 AM – 10:05 AM – Lunbin Deng
Genentec – “Making novel pain drugs by selectively targeting Nav1.7”
10:05 AM – 10:25 AM – Xian-Ping Dong
Dalhousie University – “Regulation of MTORC1 by the lysosomal Ca2+ channel TRPML1/mucolipin-1 in cellular homeostasis and human diseases”
10:25 AM – 10:55 AM – Coffee Break & Posters
IC Session: Ion Channels as Disease Targets
10:55 AM – 11:00 AM – Chair: Zhuo Huang
Peking University
11:00 AM – 11:20 AM – Zhuo Huang
Peking University – “ERG3 potassium channel-mediated suppression of neuronal intrinsic excitability and prevention of seizure generation in mice”
11:20 AM – 11:40 AM – Christopher Donald Makinson
Stanford University: School of Medicine – “Targeting voltage gated sodium channels for the treatment of epilepsy”
11:40 AM – 12:00 PM – Weiping Wang
IMM – “Discovery of Kv2.1 potassium channel selective blocker for neuroprotection”
IC Session: Structure and Function of Ion Channels
12:00 AM – 12:20 PM – Jing Li
Guangzhou University of Chinese Medicine – “Mechanosensitive ion channel protein Piezo1in vascular biology”
-End of Parallel Session 2-
12:20 PM – 12:30 PM – Closing Remarks
12:30 PM – 1:30 PM – Break + Lunch
Visit & Study Section
1:30 PM – 6:00 PM – Sino-Euro Center, Aurora Scientific park