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Applications

HIGH THROUGHPUT SCREENING ASSAY FOR ACID-SENSING ION CHANNELS

Acid-sensing ion channels (ASICs) are members of the amiloridesensitive epithelial Na+-channel/degenerin superfamily (ENaC/DEG). These ligand-gated ion channels areactivated by protons, which are released during tissue acidosis (increase in extracellular acidity). Tissue acidosis, which is evidence...
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Ion Channel Retreat 2014: Ligand-gated channels

This year's event is shaping up to be especially interesting with topics such as ion channels in disease and pain, ion channel screening technologies for assessment of cardiac safety and toxicology, structure and function of ion channels, and new this year a session focusing on transporter molecules and their roles with ion channels.
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