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bCUBE real-time PCR machine

PRODUCT INFORMATION


    Keeping a firm ‘GRASP’ on the RT-PCR workflow

    HYRIS™ bCUBE™, a palm-sized device which is capable of running RT-PCR as well as data reporting is now available. With wifi-connectivity, this plug-and-play device handles RT-PCR workflow within 2 hours anywhere at any time. Ideal for remote locations.

    The HYRIS™ bCUBE™ is a compact, CE and IVD-certified RT-PCR device built for rapid, remote testing. With wireless connectivity, plug-and-play setup, and built-in data analysis, it delivers reliable results in under 90 minutes—no calibration required.

    Perfect for point-of-care and field use, bCUBE runs PCR, isothermal amplification, and melting curve analysis with high precision. It processes up to 36 samples and is fully compatible with HYRIS bKIT™, bAPP™, and bDATA™.

    • Palm-sized: 100 × 100 × 120 mm, ~1 kg
    • Auto-adaptive thermal control with ultra-fine ramping
    • High-speed detection (<0.05°C sampling)
    • 2–3 wavelength detection
    • Full WiFi support and real-time analysis via integrated apps
    DIMENSION100x100x120mm
    WEIGHT1.15kg
    USER INTERFACEHYRIS bAPPTM(Multi Platform)/HYRIS bPANELTM(Windows PC)
    COMMUNICATION INTERFACEWifi, Ethernet
    SAMPLE NUMBER16 Samples or 36 Samples depending on the cartridge format
    REACTION VOLUME10-25ul
    LIGHT SOURCESHigh Brightness LEDs – 2 or 3 wavelengths
    EXCITATION WAVELENGTH472nm and 530nm
    OPTICAL DETECTIONHigh-resolution low noise CMOS camera
    ACQUISITION TIME<1s – Total time for all samples
    DETECTED WAVELENGTHS572nm and 524nm
    THERMAL BLOCKPeltier module for heating and cooling
    TEMPERATURE SENSORHigh Precision NTC resistor
    TEMPERATURE RESOLUTION<0.05oC
    TEMPERATURE UNIFORMITY±0.1oC
    TEMPERATURE CONTROL RANGE20-99oC
    TEMPERATURE RAMPUp to 1.5oC/s
    POWER SUPPLY12v – DC
    POWER CONSUMPTIONMax 60W

    Alfa variant known as B.1.1.7/501Y.V1

    Beta variant known as B.1.351/501Y.V2

    Gamma variant known as P.1/501Y.V3

    Delta variant known as B.1.617

    Omicron variants known as B.1.1.529 and BA.5

    Californian variants known as B.1.429 and B.1.427

    How many samples can you run on bCUBETM?

    Two sizes of well plates are available: 16 and 36, so a maximum of 16 or 36 samples can be loaded per run.

    Is bCUBETM an open system? Can we run other kits on it rather than bKITTM?

    Yes, bCUBETM can run other brands of PCR kits; however, a protocol needs to be developed prior to the best performance.

    How do we control/operate bCUBETM, is there a separate platform to use?

    The device can be connected to computers or even phones/tablets (which have bAppTM installed) via Ethernet or Wifi. The software bAppTM will be used to operate the device.

    Where do we interpret the data?

    Users can simply review all data on bAppTM and will be able to export them anytime they want.

    How many fluorescent channels does bCUBETM have? What wavelength does it detect?

    It has two channels and can detect wavelengths at 524 and 572 nm.

    How It Works

    Get more information about bCUBE real-time PCR machine :